Medicinal Chemistry-I (Second Year B.Pharm Sem IV)

In the last two decades, the phases of ever-growing volume and ever-changing nature of the drug information are witnessed. This is mainly due to an increase in the rate of introduction of new drugs and an increase in the number and depth of published work on both, new as well as existing drugs. Above facts necessitated addition of all recent information wherever it deserves, while presenting the first edition of this book. New chapters on drugs used in neurodegenerative diseases and Anti-migraine agents have been included.

The book was appreciated in all corners of the profession. It has now attained the reputation as a class-room text book for undergraduate and post-graduate students of pharmacy. However, our aim remains the same as to present a review of basic principles of medicinal chemistry and to explain the effects of structural modifications of the lead nucleus on the selectivity of action, duration of action and on the intensity and frequency of adverse-effects.

1. Introduction To Medicinal Chemistry

2. Physico-Chemical Parameters And Drug Action

3. Drug Metabolism

4. Drugs Acting On Autonomic Nervous System

5. Sympathomimetic Agents

6. Cholinergic Neurotransmitters

7. Sedatives And Hypnotics

8. Antipsychotics

9. Anticonvulsant Drugs

10. General Anesthetics

11. Opioid Analgetics

12. Anti-Inflammatory Analgesics

Sample Questions

Synthesis